BDBM50425005 CHEMBL2312188

SMILES CNc1nc(C)c(s1)-c1nc(Nc2cccc(O)c2)ncc1C#N

InChI Key InChIKey=NYRVLHGVDPPWJS-UHFFFAOYSA-N

Data  4 KI

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425005   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50425005(CHEMBL2312188)Copy SMILESCopy InChI

Affinity DataKi:  12nMAssay Description:Inhibition of CDK2/Cyclin A (174 to 432 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI